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CD81 抗体

The 仓鼠 单克隆 anti-CD81 antibody is suitable to detect CD81 in samples from 小鼠. It has been validated for FACS.
产品编号 ABIN212888
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD81 抗体 (ABIN212888)

抗原

See all CD81 抗体
CD81

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD81 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

Eat2
  • 特异性

    Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and non-killer cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells.

    纯化方法

    Protein G purified

    免疫原



    Type of Immunogen: Native protein

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
  • 抗原

    CD81

    别名

    CD81

    背景

    Name/Gene ID: CD81
    Family: Tetraspan

    Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

    基因ID

    975

    UniProt

    P60033

    途径

    Inositol Metabolic Process, Hepatitis C
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