Transferrin 抗体 (N-Term)
Quick Overview for Transferrin 抗体 (N-Term) (ABIN211539)
抗原
See all Transferrin (TF) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Anti transferrin clone HTF-14 is specific for the N-terminal domain of human transferrin and has been shown to block binding of transferrin to the transferrin receptor (CD71). Clone HTF-14 is not able to recognize receptor bound transferrin. Clone HTF-14 recognizes a conformational epitope in a loop of the N lobe of transferrin involving the critical Lys-144 residue, also essential for binding of the N lobe to the transferrin receptor Transferrin is a 77 kD plasma protein synthesized by the liver involved with the transport of iron. Each transferrin molecule has two domains, both with facility to carry 2 ferric ions. The iron/transferrin complex is essential for haemoglobin synthesis and certain types of cell division.
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无交叉反应
- 牛, 绵羊, 犬, 马
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纯化方法
- Protein A purified
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免疫原
- Purified porcine transferrin ( N-TERMINAL ).
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.2, 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Transferrin (TF)
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别名
- TF / Transferrin
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背景
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Name/Gene ID: TF
Synonyms: TF, PRO1557, Serotransferrin, Siderophilin, TFQTL1, Beta-1 metal-binding globulin, Transferrin, PRO2086 -
基因ID
- 7018
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UniProt
- P02787
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途径
- Transition Metal Ion Homeostasis
抗原
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