TBK1 抗体
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北京 101111
Quick Overview for TBK1 抗体 (ABIN209092)
抗原
See all TBK1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- NF-kB (nuclear factor kB) is sequestered in the cytoplasm by IkB family of inhibitory proteins that mask the nuclear localization signal of NF-kB thereby preventing translocation of NF-kB to the nucleus (1). External stimuli such as tumor necrosis factor or other cytokines results in phosphorylation and degradation of IkB releasing NF-kB dimers. NF-kB dimer subsequently translocates to the nucleus and activates target genes. Synthesis of IkBa is autoregulated (2). IkB proteins are phosphory.
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纯化方法
- Protein G purified
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免疫原
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Type of Immunogen: Native protein -
亚型
- IgG1 kappa
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应用备注
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Approved: WB (1 - 2 μg/mL)
Usage: Suitable for use in Western Blot. Western Blot: 1-2 μg/mL. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.05 % BSA, 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- TBK1 (TANK-Binding Kinase 1 (TBK1))
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别名
- NAK / TBK1
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背景
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Name/Gene ID: TBK1
Subfamily: IKAPPAB
Family: Protein Kinase
Synonyms: TBK1, T2K, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, TANK-binding kinase 1 -
基因ID
- 29110
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UniProt
- Q9UHD2
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
抗原
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