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CD74 抗体 (C-Term) (FITC)

CD74 适用: 人 FACS 宿主: 小鼠 Monoclonal BU45 FITC
产品编号 ABIN207706
发货至: 中国
  • 抗原 See all CD74 抗体
    CD74 (HLA-DR-gamma (CD74))
    抗原表位
    • 21
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    C-Term
    适用
    • 177
    • 64
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    宿主
    • 116
    • 79
    • 3
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    小鼠
    克隆类型
    • 131
    • 67
    • 2
    单克隆
    标记
    • 66
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    This CD74 antibody is conjugated to FITC
    应用范围
    • 122
    • 105
    • 76
    • 41
    • 36
    • 36
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    • 17
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    Flow Cytometry (FACS)
    特异性
    Recognizes human CD74, a type II transmembrane protein, which is also known as the MHC class II associated invariant chain. The Recognizes 33, 35 and 41 kD isoforms of CD74. The CD74 Molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinoma. Expression of CD74 is primarily intracellular with moderate expression at the cell surface of B cells and monocytes. The Bu45 antibody binds to an epitope within the extracytoplasmic domain of the CD74 Molecule, which is distal from the C-terminus. *Membrane permeabilization may enhance CD74 staining on monocytes but is not required when staining lymphocytes. XXX recommend the use of Leucoperm (product code BUF09) for this purpose.
    纯化方法
    Protein G purified
    免疫原
    B lymphoblastoid cell line HFB1.

    Type of Immunogen: Cells
    克隆位点
    BU45
    亚型
    IgG1
    Top Product
    Discover our top product CD74 Primary Antibody
  • 应用备注
    Approved: Flo (1:1 - 1:5)

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    CD74 (HLA-DR-gamma (CD74))
    别名
    CD74 / CLIP (CD74 产品)
    别名
    DHLAG antibody, HLADG antibody, II antibody, Ia-GAMMA antibody, CLIP antibody, Ii antibody, INVG34 antibody, Iclp-1 antibody, iclp1 antibody, wu:fb11f09 antibody, wu:fb12a01 antibody, wu:fb13d06 antibody, wu:fk94e07 antibody, Iclp-2 antibody, cd74 antibody, iclp2 antibody, zgc:123161 antibody, CD74 molecule antibody, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) antibody, CD74 molecule, major histocompatibility complex, class II invariant chain a antibody, CD74 molecule, major histocompatibility complex, class II invariant chain b antibody, CD74 antibody, Cd74 antibody, cd74a antibody, cd74b antibody
    背景
    Name/Gene ID: CD74

    Synonyms: CD74, CD74 antigen, DHLAG, HLADG, HLA-DR-gamma, Ia-associated invariant chain, p33, MHC HLA-DR gamma chain, Ia-GAMMA
    基因ID
    972
    UniProt
    P04233
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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