CFP 抗体
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北京 101111
Quick Overview for CFP 抗体 (ABIN206668)
抗原
See all CFP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human factor P, a 53 kD glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections. Is reported to inhibit the function of factor P. Removal of Sodium Azide is recommended prior to use in functional assays. XXX recommend the use of EQU003 for this purpose.
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纯化方法
- Protein A purified
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免疫原
- Native purified factor P from human serum.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Borate buffered saline, pH 8.2, 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CFP (Complement Factor P (CFP))
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别名
- Properdin / CFP
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背景
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Name/Gene ID: CFP
Synonyms: CFP, Complement factor P, Complement factor properdin, PFC, PFD, Properidin, BFD, Properdin, Properdin P factor, complement -
基因ID
- 5199
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UniProt
- P27918
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途径
- Complement System
抗原
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