CD80 抗体
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- 抗原 See all CD80 抗体
- CD80
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This CD80 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
- 纯化方法
- Protein G purified
- 免疫原
- BCL1 cells expressing CD80.
- 克隆位点
- RM80
- 亚型
- IgG2a
- Top Product
- Discover our top product CD80 Primary Antibody
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- 应用备注
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Approved: Flo (1:10 - 1:50), IHC, IHC-Fr
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. - 说明
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Target Species of Antibody: Mouse
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- 抗原
- CD80
- 别名
- CD80 / B7 (CD80 产品)
- 背景
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Name/Gene ID: CD80
Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1 - 基因ID
- 941
- UniProt
- P33681
- 途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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