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CD80 抗体

CD80 适用: 小鼠 FACS, IHC, IHC (fro) 宿主: 大鼠 Monoclonal RM80 unconjugated
产品编号 ABIN206612
发货至: 中国
  • 抗原 See all CD80 抗体
    CD80
    适用
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    • 95
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    小鼠
    宿主
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    大鼠
    克隆类型
    • 132
    • 80
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    单克隆
    标记
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    This CD80 antibody is un-conjugated
    应用范围
    • 124
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    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes mouse CD80 (B7-1), a 60kD cell surface glycoprotein which is a member of the CD28/B7 family. In mice, CD80 is expressed on monocytes, peritoneal macrophages and dendritic cells, and expression may be significantly increased upon B lymphocytes by LPS and by IL-4. CD80 has been identified as a ligand for CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4), two structurally similar molecules expressed on T cells. CD28 and CTLA4 are two receptors that have essential but opposing functions in T-cell stimulation. The Interaction of CD80 with CD28 stimulates and sustains T cell responses, whereas the interaction of CD80 with CTLA4 is reported to inhibit T-cell responses.
    纯化方法
    Protein G purified
    免疫原
    BCL1 cells expressing CD80.
    克隆位点
    RM80
    亚型
    IgG2a
    Top Product
    Discover our top product CD80 Primary Antibody
  • 应用备注
    Approved: Flo (1:10 - 1:50), IHC, IHC-Fr

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.
    说明

    Target Species of Antibody: Mouse

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原
    CD80
    别名
    CD80 / B7 (CD80 产品)
    背景
    Name/Gene ID: CD80

    Synonyms: CD80, Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CD80 antigen, LAB7, CD80 Molecule, CTLA-4 counter-receptor B7.1
    基因ID
    941
    UniProt
    P33681
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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