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GZMB 抗体

GZMB 适用: 人, 猴, 猕猴 IHC, ELISA, FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal GB11 unconjugated
产品编号 ABIN206367
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    适用
    • 117
    • 49
    • 24
    • 9
    • 4
    • 1
    • 1
    • 1
    人, 猴, 猕猴
    宿主
    • 78
    • 42
    • 1
    小鼠
    克隆类型
    • 76
    • 45
    单克隆
    标记
    • 75
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 1
    • 1
    • 1
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    This GZMB antibody is un-conjugated
    应用范围
    • 71
    • 41
    • 36
    • 36
    • 17
    • 17
    • 16
    • 14
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    • 9
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    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes the serine protease Granzyme B, which is important in the induction of apoptosis in target cells by cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell, Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a capture reagent in ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (MCA2119B) as detection reagent.
    纯化方法
    Protein A purified
    免疫原
    Purified human Granzyme B.

    Type of Immunogen: Purified protein
    克隆位点
    GB11
    亚型
    IgG1
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Approved: ELISA (2 - 5 μg/mL), Flo (1:10 - 1:100), IHC, IHC-Fr, IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. ELISA: This antibody has been reported to function as a capture reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with biotin conjugated clone GB10 (LS-C44294) as detection reagent.
    说明

    Target Species of Antibody: Human

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Tris buffered saline, 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    avoid freeze thaw cycles. Store undiluted.
    储存条件
    4 °C,-20 °C
    储存方法
    Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
  • 抗原
    GZMB (Granzyme B (GZMB))
    别名
    GZMB / Granzyme B (GZMB 产品)
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景
    Name/Gene ID: GZMB
    Subfamily: Serine S1
    Family: Protease

    Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2
    基因ID
    3002
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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