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GZMB 抗体 (Biotin)

This anti-GZMB antibody is a 小鼠 单克隆 antibody detecting GZMB in IHC, ELISA, FACS, IP 和 IHC (fro). Suitable for 人, 猴 和 猕猴.
产品编号 ABIN206366
发货至: 中国

Quick Overview for GZMB 抗体 (Biotin) (ABIN206366)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

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人, 猴, 猕猴

宿主

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小鼠

克隆类型

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  • 87
单克隆

标记

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This GZMB antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

GB10
  • 特异性

    Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (MCA2120) as capture reagent.

    纯化方法

    Protein A purified

    免疫原

    Purified human Granzyme B.

    Type of Immunogen: Purified protein

    亚型

    IgG1
  • 应用备注

    Approved: ELISA (1 μg/mL), Flo, IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. ELISA: This antibody has been reported to function as a detection reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with GB11 (LS-C44295) as capture reagent.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    TBS, BSA, 0.001 % Thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    GZMB (Granzyme B (GZMB))

    别名

    GZMB / Granzyme B

    背景

    Name/Gene ID: GZMB
    Subfamily: Serine S1
    Family: Protease

    Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2

    基因ID

    3002

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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