GZMB 抗体 (Biotin)
Quick Overview for GZMB 抗体 (Biotin) (ABIN206366)
抗原
See all GZMB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs). Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death. Has been reported to function as a detection reagent in ELISA assays for soluble Granzyme B in conjunction with GB11 (MCA2120) as capture reagent.
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纯化方法
- Protein A purified
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免疫原
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Purified human Granzyme B.
Type of Immunogen: Purified protein -
亚型
- IgG1
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应用备注
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Approved: ELISA (1 μg/mL), Flo, IHC, IHC-Fr, IP
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. ELISA: This antibody has been reported to function as a detection reagent in sandwich ELISA assays for soluble Granzyme B in conjunction with GB11 (LS-C44295) as capture reagent. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- TBS, BSA, 0.001 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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别名
- GZMB / Granzyme B
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背景
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Name/Gene ID: GZMB
Subfamily: Serine S1
Family: Protease
Synonyms: GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2 -
基因ID
- 3002
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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