Haptoglobin 抗体 (FITC)
Quick Overview for Haptoglobin 抗体 (FITC) (ABIN1992508)
抗原
See all Haptoglobin (HP) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
 - Caprylic Acid Ammonium Sulfate Precipitation
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免疫原
 - Recombinant rat Haptoglobin protein
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亚型
 - IgG
 
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应用备注
 - Optimal working concentration should be determinde by the investigator.
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限制
 - 仅限研究用
 
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状态
 - Liquid
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缓冲液
 - 0.03 % Proclin 300, 53 % Glycerol, 0.01 M PBS, pH 7.4
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储存液
 - ProClin
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注意事项
 - This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
 - Avoid repeated freeze.
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储存条件
 - -20 °C/-80 °C
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储存方法
 - Upon delivery aliquot and store at -20 °C or -80 °C.
 
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- Haptoglobin (HP)
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别名
 - Haptoglobin
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背景
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                        As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway?.Uncleaved haptoglogin, also known as zonulin, plays a role in intestinal permeability, allowing intercellular tight junction disassembly, and controlling the equilibrium between tolerance and immunity to non-self antigens.
Synonyms: Liver regeneration-related protein LRRG173, Zonulin,Hp,Ba1-647 - 
                                            
UniProt
 - P06866
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途径
 - Transition Metal Ion Homeostasis
 
抗原
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