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RNASEL 抗体 (AA 330-741) (FITC)

RNASEL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal FITC
产品编号 ABIN1991048
发货至: 中国
  • 抗原 See all RNASEL 抗体
    RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
    抗原表位
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 330-741
    适用
    • 19
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 27
    • 5
    • 1
    克隆类型
    • 29
    • 4
    多克隆
    标记
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    This RNASEL antibody is conjugated to FITC
    应用范围
    • 25
    • 25
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human 2-5A-dependent ribonuclease protein (330-741AA)
    亚型
    IgG
    Top Product
    Discover our top product RNASEL Primary Antibody
  • 应用备注
    Optimal working concentration should be determinde by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RNASEL (Ribonuclease L (2',5'-Oligoisoadenylate Synthetase-Dependent) (RNASEL))
    别名
    RNASEL (RNASEL 产品)
    别名
    E230029I04Rik antibody, PRCA1 antibody, RNS4 antibody, ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) antibody, ribonuclease L antibody, Rnasel antibody, RNASEL antibody
    背景

    Background: Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes. RNASEL mediated apoptosis is the result of a JNK-dependent stress-response pathway leading to cytochrome c release from mitochondria and caspase-dependent apoptosis. Therefore, activation of RNASEL could lead to elimination of virus infected cells under some circumstances. Might play a central role in the regulation of mRNA turnover.

    Aliases: 2 5A dependent ribonuclease antibody, 2 5A dependent RNase antibody, 2' 5' oligoisoadenylate synthetase dependent antibody, 2-5A-dependent ribonuclease antibody, 2-5A-dependent RNase antibody, DKFZp781D08126 antibody, Interferon induced 2 5A dependent RNase antibody, MGC104972 antibody, MGC133329 antibody, PRCA 1 antibody, PRCA1 antibody, Ribonuclease 4 antibody, Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) antibody, Ribonuclease L antibody, Ribonuclease4 antibody, RibonucleaseL antibody, RN5A_HUMAN antibody, RNase L antibody, Rnasel antibody, RNS 4 antibody, RNS4 antibody

    UniProt
    Q05823
    途径
    Hepatitis C
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