IL4 Receptor 抗体 (Extracellular Domain)
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- 抗原 See all IL4 Receptor (IL4R) 抗体
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
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抗原表位
- Extracellular Domain
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL4 Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Recognizes human Interleukin-4 receptor subunit alpha, also known as CD124. CD124 is a 825 amino acid ~90kD type I single pass transmembrane glycoprotein bearing a single domain. Interleukin-4 Receptor form a heterodimeric complex with the, referred to as the IL-4 type-1 complex. The alpha subunit can also form the type-II complex through association with the IL-13 receptor alpha 1 subunit. The IL-4R complex acts as a receptor for both interleukin-4 and interleukin-13. IL-4 R is expressed by B cells, T cells, monocytes and macrophages. Is reported to block human cell surface IL-4 receptor mediated bioactivities induced by IL-4 or IL-13. An ND50 was observed at approximately 5-20 ng/mL in the presence of 0.2 ng/mL of IL-4 using the factor dependant human erythroleukemic cell line, TF-1.
- 纯化方法
- Protein A purified
- 免疫原
- Sf 21-derived, recombinant human interleukin 4 receptor, extracellular domain.
- 克隆位点
- 49-20
- 亚型
- IgG1
- Top Product
- Discover our top product IL4R Primary Antibody
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- 应用备注
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Approved: ELISA (1:500 - 1:2000), Flo (1:20 - 1:80), IHC, IHC-P (1:40 - 1:125), WB (1:250 - 1:1000)
Usage: Western Blot: Will detect human IL-4 R under non-reducing conditions. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, 0.09 % sodium azide, 10 % trehalose
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- 抗原
- IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
- 别名
- IL4R / CD124 (IL4R 产品)
- 背景
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Name/Gene ID: IL4R
Family: Interleukin
Synonyms: IL4R, CD124, CD124 antigen, IL-4RA, IL4R nirs variant 1, IL4RA, Interleukin 4 receptor, IL-4 receptor subunit alpha, IL-4R subunit alpha, IL-4R-alpha - 基因ID
- 3566
- 途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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