PDGFRA 抗体 (Extracellular Domain)
Quick Overview for PDGFRA 抗体 (Extracellular Domain) (ABIN198260)
抗原
See all PDGFRA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Extracellular Domain
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特异性
- Recognizes the human platelet-derived growth factor receptor alpha, a 1089 amino acid, ~180 kD single pass type I transmembrane glycoprotein. PDGF is a major serum mitogen that can exist as a homo- or heterodimeric protein consisting of disulphide-linked PDGF-A and PDGF-B chains. The PDGF-AA, PDGF-BB and PDGF-AB isoforms have been shown to bind to two distinct cell surface PDGF receptors with different affinities. Whereas PDGF receptor alpha binds all three isoforms with high affinity, PDGF R beta binds PDGF-BB and AB but not PDGF-AA. Both PDGF receptor alpha and beta are members of the class III subfamily of receptor tyrosine kinases. Has been reported for use in functional studies. The ND50 was determined as 0.2-0.6 μg/mL for blocking 10 ng/mL of PDGF-AA biological activity on a quiescent confluent cell culture of human WS1 cells.
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纯化方法
- Protein G purified
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免疫原
- Purified recombinant human platelet-derived growth factor (PDGF) receptor alpha (extracellular domain), derived from the insect cell line Sf21.
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亚型
- IgG1
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anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibody
PDGFRA 适用: 人 ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 5B11G5 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 361-528) antibodyPDGFRA 适用: 人 ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 8E12F2 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 331-719) antibodyPDGFRA 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-210) antibodyPDGFRA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 179-361) antibodyPDGFRA 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1A10A8 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 698-727) antibodyPDGFRA 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB11101 unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1048-1077) antibodyPDGFRA 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1021-1089) antibodyPDGFRA 适用: 人, 小鼠, 大鼠, 犬 ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 1-1089) antibodyPDGFRA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Platelet Derived Growth Factor Receptor alpha (PDGFRA) (AA 25-218) antibodyPDGFRA 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4H1-1C9 unconjugated
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应用备注
- Approved: ELISA (0.5 - 1 μg/mL), IHC, IHC-P (10 - 20 μg/mL), WB (1 - 2 μg/mL)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide, 1.5 % Trehalose
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- avoid freeze thaw cycles. Store undiluted.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles. Store undiluted.
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- PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
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别名
- PDGFRA / PDGFR alpha
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背景
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Name/Gene ID: PDGFRA
Subfamily: PDGF Receptor
Family: Protein Kinase
Synonyms: PDGFRA, CD140A, CD140a antigen, PDGFalphaR, PDGFR2, PDGFRalpha, AlphaPDGFR, RHEPDGFRA, PDGF receptor alpha, PDGFR-2, PDGFRA/BCR fusion, APDGFR, Pdgf alpha-receptor, PDGF-R-alpha, PDGFR-alpha -
基因ID
- 5156
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
抗原
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