CD300E 抗体 (APC)
(2 references)Quick Overview for CD300E 抗体 (APC) (ABIN1981879)
抗原
See all CD300E 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD300e APC
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特异性
- The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- CD300e-HA-transfected cells
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亚型
- IgG1 kappa
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anti-CD300e Molecule (CD300E) antibody
CD300E 适用: 人 WB, FACS, IP 宿主: 小鼠 Monoclonal UP-H2 unconjugated
anti-CD300e Molecule (CD300E) antibody (FITC)CD300E 适用: 人 FACS 宿主: 小鼠 Monoclonal UP-H2 FITC
anti-CD300e Molecule (CD300E) antibodyCD300E 适用: 人 WB, FACS, IP, Func 宿主: 小鼠 Monoclonal UP-H2 unconjugated
anti-CD300e Molecule (CD300E) antibody (PE)CD300E 适用: 人 FACS 宿主: 小鼠 Monoclonal UP-H2 PE
anti-CD300e Molecule (CD300E) antibody (PE)CD300E 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal UP-H2 PE
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze. Avoid prolonged exposure to light.
Do not use after expiration date stamped on vial label.
Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).
: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, (2004) (PubMed).
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: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).
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- CD300E (CD300e Molecule (CD300E))
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别名
- CD300e
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背景
- CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
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基因ID
- 342510
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UniProt
- Q496F6
抗原
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