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CD300E 抗体 (PE)

CD300E 适用: 人 FACS 宿主: 小鼠 Monoclonal UP-H2 PE
产品编号 ABIN1981891
发货至: 中国
  • 抗原 See all CD300E 抗体
    CD300E (CD300e Molecule (CD300E))
    适用
    • 35
    • 8
    宿主
    • 22
    • 13
    小鼠
    克隆类型
    • 23
    • 12
    单克隆
    标记
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    This CD300E antibody is conjugated to PE
    应用范围
    • 20
    • 14
    • 12
    • 5
    • 4
    • 3
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    Flow Cytometry (FACS)
    特异性
    The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
    交叉反应 (详细)
    Human
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    CD300e-HA-transfected cells
    克隆位点
    UP-H2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD300E Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    说明

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Do not freeze. Avoid prolonged exposure to light.
    Do not use after expiration date stamped on vial label.
    Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

    Aguilar, Alvarez-Errico, García-Montero, Orfao, Sayós, López-Botet: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, (2004) (PubMed).

  • 抗原
    CD300E (CD300e Molecule (CD300E))
    别名
    CD300e (CD300E 产品)
    别名
    BC034097 antibody, CLM2 antibody, Cd300le antibody, TREM5 antibody, CD300LE antibody, CLM-2 antibody, CMRF35-A5 antibody, IREM-2 antibody, IREM2 antibody, PIgR-2 antibody, PIgR2 antibody, CD300E molecule antibody, CD300e molecule antibody, Cd300e antibody, CD300E antibody
    背景
    CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
    基因ID
    342510
    UniProt
    Q496F6
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