CD42a 抗体
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北京 101111
Quick Overview for CD42a 抗体 (ABIN1981875)
抗原
See all CD42a (GP9) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD42a Purified
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特异性
- The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
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交叉反应 （详细）
- Human, Canine (Dog)
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Human acute lymphoblastic leukemia cells
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亚型
- IgG1
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anti-Glycoprotein IX (Platelet) (GP9) (AA 1-189) antibody
GP9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein IX (Platelet) (GP9) antibody (FITC)GP9 适用: 人, 犬 FACS 宿主: 小鼠 Monoclonal GR-P FITC
anti-Glycoprotein IX (Platelet) (GP9) (AA 17-147) antibodyGP9 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4E2G7 unconjugated
anti-Glycoprotein IX (Platelet) (GP9) (AA 17-88) antibodyGP9 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein IX (Platelet) (GP9) antibody (APC)GP9 适用: 人, 犬 FACS 宿主: 小鼠 Monoclonal GR-P APC
anti-Glycoprotein IX (Platelet) (GP9) (AA 17-147) antibodyGP9 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein IX (Platelet) (GP9) (Internal Region) antibodyGP9 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein IX (Platelet) (GP9) antibody (PE)GP9 适用: 人, 犬, Mink FACS 宿主: 小鼠 Monoclonal GRP-P PE
anti-Glycoprotein IX (Platelet) (GP9) (AA 1-177) antibodyGP9 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glycoprotein IX (Platelet) (GP9) antibody (PE)GP9 适用: 人, 犬 FACS 宿主: 小鼠 Monoclonal GR-P PE
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze. Do not use after expiration date stamped on vial label.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans." in: European journal of clinical nutrition, Vol. 65, Issue 2, pp. 234-9, (2011) (PubMed).
: "Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin." in: Heart (British Cardiac Society), Vol. 92, Issue 11, pp. 1635-8, (2006) (PubMed).
: "Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5987-96, (2000) (PubMed).
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: "Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans." in: European journal of clinical nutrition, Vol. 65, Issue 2, pp. 234-9, (2011) (PubMed).
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- CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
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别名
- CD42a
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背景
- Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9
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基因ID
- 2815
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UniProt
- P14770
抗原
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