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CD300E 抗体

There is 1 publication for this product available. The 小鼠 单克隆 anti-CD300E antibody is suitable to detect CD300E in samples from 人. It has been validated for WB, FACS 和 IP.
产品编号 ABIN1981868
发货至: 中国
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Quick Overview for CD300E 抗体 (ABIN1981868)

抗原

See all CD300E 抗体
CD300E (CD300e Molecule (CD300E))

适用

  • 29
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宿主

  • 20
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小鼠

克隆类型

  • 21
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单克隆

标记

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This CD300E antibody is un-conjugated

应用范围

  • 15
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Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

克隆位点

UP-H2
  • 原理

    Anti-Hu CD300e Purified

    交叉反应 (详细)

    Human

    产品特性

    The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    CD300e-HA-transfected cells

    亚型

    IgG1, kappa
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

  • 抗原

    CD300E (CD300e Molecule (CD300E))

    别名

    CD300e

    背景

    CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

    基因ID

    342510

    UniProt

    Q496F6
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