TLR4 抗体
Quick Overview for TLR4 抗体 (ABIN198155)
抗原
See all TLR4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts preferentially, especially in Flow Cytometry, with human TLR4 (CD284) that is associated with MD-2. This clone is a TLR4 (CD284) function-blocking antibody that is useful for studies on the role of TLR4 (CD284) as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to precipitate TLR4 (100kD).
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纯化方法
- Purified
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免疫原
- Human TLR4.
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亚型
- IgG2a
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应用备注
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Approved: Flo, IHC, IHC-Fr, IP, Neut
Usage: Suitable for use in Flow Cytometry, Immunoprecipitation, and Neutralization (can be used as antagonist for TLR4, it blocks LPS-induced cytokine production). Note: Before use in biological assays, the product must be sterile-filtered and depending on the concentration to be used, dialyzed against culture medium to remove the sodium azide added. -
说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.1 % BSA, 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- TLR4 (Toll-Like Receptor 4 (TLR4))
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别名
- TLR4
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背景
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Name/Gene ID: TLR4
Family: Toll-like Receptor
Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll -
基因ID
- 7099
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UniProt
- O00206
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
抗原
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