PKC delta 抗体 (AA 643-647)
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Quick Overview for PKC delta 抗体 (AA 643-647) (ABIN197564)
抗原
See all PKC delta (PKCd) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 643-647
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特异性
- This antibody detects endogenous levels of total PKC-delta protein.
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纯化方法
- Immunoaffinity Chromatography using epitope-specific immunogen.
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免疫原
- Peptide sequence around amino acids 643~647 (R-L-Sp-Y-S) derived from Human PKC- delta
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anti-Protein Kinase C, delta (PKCd) (AA 477-676) antibody
PKCd 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) antibodyKD Validated PKCd 适用: 小鼠 WB, IF (p), FACS 宿主: 兔 Monoclonal 24GB4485 unconjugated Recombinant Antibody
anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibodyPKCd 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 6A2 unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 577-676) antibodyPKCd 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Protein Kinase C, delta (PKCd) (pTyr313) antibodyPKCd 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (C-Term) antibodyPKCd 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) antibodyKD Validated PKCd 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2410 unconjugated Recombinant Antibody
anti-Protein Kinase C, delta (PKCd) (pSer645) antibodyPKCd 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (pTyr64) antibodyPKCd 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, delta (PKCd) (AA 1-676) antibodyPKCd 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1/500approx. 1/1000. Immunofluorescence: 1/100approx. 1/200. Immunohistochemistry on Paraffin-Embedded Sections: 1/50approx. 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- PKC delta (PKCd) (Protein Kinase C, delta (PKCd))
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别名
- PRKCD
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背景
- Protein Kinase C delta (PKC delta) is a 78 kDa member of the novel group (nPKCs: sensitive to diacylglycerol, phosphatidylserine, and phorbol esters) of the PKC family of serine/threonine kinases that are involved in a wide range of physiological processes including mitogenesis, cell survival and transcriptional regulation. PKC delta is an ubiquitously expressed PKC isozyme that has been implicated in the regulation of multiple cellular processes including cell cycle progression and apoptosis. Autophosphorylation of serine 664 (serine 662 in mouse and rat) contributes to PKC delta activity. Serum dependent phosphorylation of serine 664 is mediated by mTOR pathway, is protected from dephosphorylation by phosphorylated threonine 505 in the activation loop, and is implicated in prolactin signaling.Synonyms: PKC delta, PKC-delta, PKCD, Protein kinase C delta type
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基因ID
- 5580
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NCBI登录号
- NP_006245
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UniProt
- Q05655
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途径
- Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism
抗原
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