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Cortactin 抗体 (Tyr466)

Name: Cortactin 抗体 (Tyr466)
SKU: ABIN197532
Availability: OutOfStock

This anti-Cortactin antibody is a 兔多克隆 antibody detecting Cortactin in WB 和 IHC (p). Suitable for 小鼠.

Image no. 2 for anti-Cortactin (CTTN) (Tyr466) antibody (ABIN197532) (Cortactin 抗体 (Tyr466))

Image no. 1 for anti-Cortactin (CTTN) (Tyr466) antibody (ABIN197532) (Cortactin 抗体 (Tyr466))

2 images

产品编号 ABIN197532

发货至: 中国

Quick Overview for Cortactin 抗体 (Tyr466) (ABIN197532)

抗原

See all Cortactin (CTTN) 抗体

Cortactin (CTTN)

适用

小鼠

宿主

兔

克隆类型

多克隆

标记

This Cortactin antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Discover our top product CTTN Primary Antibody

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Tyr466

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

免疫原

The antiserum was produced against synthesized non-phosphopeptide derived from mouse Cortactin around the phosphorylation site of tyrosine 466 (P-V-YP-E-T).
anti-Cortactin (CTTN) (N-Term) antibody
KO Validated CTTN 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (AA 214-513) antibody
CTTN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) antibody
CTTN 适用: 人 WB, IHC, IP, IF 宿主: 兔 Monoclonal unconjugated

anti-Cortactin (CTTN) (pTyr466) antibody
CTTN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (AA 341-450) antibody
CTTN 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2B5 unconjugated

anti-Cortactin (CTTN) antibody
CTTN 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 4C6 unconjugated

anti-Cortactin (CTTN) (AA 1-509) antibody
CTTN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (AA 1-509) antibody
CTTN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (pTyr421) antibody
CTTN 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cortactin (CTTN) (N-Term) antibody
Verified CTTN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

应用备注

Western Blot: 1: 500approx. 1: 1000. Immunohistochemistry: 1: 50-1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C
抗原

Cortactin (CTTN)

别名

Cortactin

背景

Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino terminal tandem repeats of a unique 37 amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha helical structure followed by a proline rich region. Between the proline rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr421, Tyr470, and Tyr486). In vitro, cortactin binds to and cross links F actin into meshworks.Synonyms: Amplaxin, CTTN, EMS1, Oncogene EMS1

基因ID

10090

UniProt

Q60598

途径

MAPK Pathway