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HDAC5 抗体 (AA 496-500)

The 兔 多克隆 anti-HDAC5 antibody (ABIN197340) specifically detects HDAC5 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN197340
发货至: 中国
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Quick Overview for HDAC5 抗体 (AA 496-500) (ABIN197340)

抗原

See all HDAC5 抗体
HDAC5 (Histone Deacetylase 5 (HDAC5))

适用

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宿主

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克隆类型

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多克隆

标记

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This HDAC5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 496-500

    特异性

    HDAC5 antibody AP02669PU detects endogenous levels of total HDAC5 protein.

    纯化方法

    Immunoaffinity Chromatography using epitope-specific immunogen.

    免疫原

    Peptide Sequenece around amino acids 496~500 (T-Q-S-S-P) derived from Human HDAC5.
  • 应用备注

    Suitable for use in Western blot (1: 500-1: 1000) and Immunohistochemistry (1: 50-1: 100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    HDAC5 (Histone Deacetylase 5 (HDAC5))

    别名

    HDAC5

    背景

    HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence.Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.Synonyms: Antigen NY-CO-9, HD5, Histone deacetylase 5, KIAA0600

    基因ID

    10014

    NCBI登录号

    NP_001015053

    UniProt

    Q9UQL6

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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