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Paxillin 抗体 (pTyr31)

The 兔多克隆 anti-Paxillin antibody is suitable to detect Paxillin in samples from 人. It has been validated for WB.

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产品编号 ABIN196941

发货至: 中国

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Quick Overview for Paxillin 抗体 (pTyr31) (ABIN196941)

抗原

See all Paxillin (PXN) 抗体

Paxillin (PXN)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Paxillin antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PXN Primary Antibody

抗原表位
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23

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pTyr31

特异性

Paxillin antibody detects endogenous levels of Paxillin only when phosphorylated at tyrosine 31.

纯化方法

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

免疫原

The antiserum was produced against synthesized phosphopeptide derived from human Paxillin around the phosphorylation site of tyrosine 31 (T-P-YP-S-Y).
anti-Paxillin (PXN) (AA 347-578) antibody
PXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 201-461) antibody
PXN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 327-568) antibody
PXN 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 9-570) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 456-472) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) antibody
KD Validated PXN 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2690 unconjugated Recombinant Antibody

anti-Paxillin (PXN) (AA 456-472), (C-Term) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (pTyr118) antibody
PXN 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Paxillin (PXN) (AA 1-262) antibody
PXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

应用备注

Western Blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

-20 °C
抗原

Paxillin (PXN)

别名

Paxillin / PXN

背景

Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691

基因ID

5829

NCBI登录号

NP_001074324

UniProt

P49023

途径

MAPK Pathway, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling