HEXIM1 抗体
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北京 101111
Quick Overview for HEXIM1 抗体 (ABIN1944936)
抗原
See all HEXIM1 抗体适用
宿主
克隆类型
标记
应用范围
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亚型
- IgG
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anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (C-Term) antibody
Verified HEXIM1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) antibodyKD Validated HEXIM1 适用: 人 WB, IF (p), FACS 宿主: 小鼠 Monoclonal 25GB650 unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 1-359) antibodyHEXIM1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1H5 unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) antibodyHEXIM1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 1-359) antibodyHEXIM1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4G4 unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 210-359) antibodyHEXIM1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) antibodyHEXIM1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 194-222) antibodyHEXIM1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) antibodyHEXIM1 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2416C2a unconjugated
anti-Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1) (AA 18-46), (N-Term) antibodyHEXIM1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB33760 unconjugated
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应用备注
- IF: 1:100. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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储存条件
- 4 °C,-20 °C
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: "Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors." in: Cancer research, Vol. 63, Issue 16, pp. 5151-8, (2003) (PubMed).
: "Suppression of NF-kappaB-dependent gene expression by a hexamethylene bisacetamide-inducible protein HEXIM1 in human vascular smooth muscle cells." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 8, Issue 2, pp. 95-107, (2003) (PubMed).
: "Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA." in: Molecular cell, Vol. 12, Issue 4, pp. 971-82, (2003) (PubMed).
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: "Identification of a novel inhibitor of breast cell growth that is down-regulated by estrogens and decreased in breast tumors." in: Cancer research, Vol. 63, Issue 16, pp. 5151-8, (2003) (PubMed).
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- HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))
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别名
- HEXIM1
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背景
- Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation. May also regulate NF-kappa-B, ESR1, NR3C1 and CIITA-dependent transcriptional activity.
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分子量
- 40623 Da
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基因ID
- 10614
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UniProt
- O94992
抗原
-
