SP1 抗体 (AA 1-250)
(2 references)Quick Overview for SP1 抗体 (AA 1-250) (ABIN1944791)
抗原
See all SP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1-250
-
纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
免疫原
- This SP1 antibody is generated from a mouse immunized with a recombination protein from the human SP1.
-
亚型
- IgG1 kappa
-
-
anti-Sp1 Transcription Factor (SP1) (pThr453) antibody
SP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (C-Term) antibodySP1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 522-618) antibodySP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4B11 unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-198) antibodySP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A5 unconjugated
anti-Sp1 Transcription Factor (SP1) antibodySP1 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 89-199) antibodySP1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4H6 unconjugated
anti-Sp1 Transcription Factor (SP1) (pThr739) antibodySP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 420-620) antibodySP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sp1 Transcription Factor (SP1) (AA 677-707), (C-Term) antibodySP1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17350 unconjugated
-
-
应用备注
- IF: 1:25. WB: 1:1000. FC: 1:25
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
: "Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing." in: The Journal of biological chemistry, Vol. 275, Issue 48, pp. 38067-72, (2000) (PubMed).
: "Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain." in: Cell, Vol. 51, Issue 6, pp. 1079-90, (1988) (PubMed).
-
: "Heterogeneous Sp1 mRNAs in human HepG2 cells include a product of homotypic trans-splicing." in: The Journal of biological chemistry, Vol. 275, Issue 48, pp. 38067-72, (2000) (PubMed).
-
- SP1 (Sp1 Transcription Factor (SP1))
-
别名
- SP1
-
背景
- Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression.
-
分子量
- 80693
-
基因ID
- 6667
-
UniProt
- P08047
-
途径
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
抗原
-
