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PLSCR1 抗体

This anti-PLSCR1 antibody is a 小鼠 单克隆 antibody detecting PLSCR1 in WB, IP, FACS 和 ICC. Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN192390
发货至: 中国

Quick Overview for PLSCR1 抗体 (ABIN192390)

抗原

See all PLSCR1 抗体
PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

适用

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大鼠

宿主

  • 19
  • 9
小鼠

克隆类型

  • 19
  • 9
单克隆

标记

  • 28
This PLSCR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)

克隆位点

13A6 [TEC-23]
  • 原理

    Anti-Rt PLSCR1 Ascites

    特异性

    The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.

    交叉反应 (详细)

    Rat

    免疫原

    Pooled lipid raft fraction isolated from RBL-2H3 cells

    亚型

    IgG2a
  • 应用备注

    Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.
    Flow cytometry: Intracellular staining.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Stabilized with 15 mM sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.
    Avoid prolonged exposure to light.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Smrz, Lebduska, Dráberová, Korb, Dráber: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).

  • 抗原

    PLSCR1 (phospholipid Scramblase 1 (PLSCR1))

    别名

    PLSCR1

    背景

    Phospholipid scramblase 1,PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.,PL scramblase 1, phospholipid scramblase 1

    基因ID

    117540

    UniProt

    P58195

    途径

    Cellular Response to Molecule of Bacterial Origin
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