PLSCR1 抗体
Quick Overview for PLSCR1 抗体 (ABIN192390)
抗原
See all PLSCR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Rt PLSCR1 Ascites
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特异性
- The antibody 13A6 [TEC-23] binds to an intracellular epitope of rat Phospholipid Scramblase 1 (PLSCR1), an 37-49 kDa protein, accelerating bidirectional movement of plasma membrane phospholipids under conditions of elevated calcium.
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交叉反应 (详细)
- Rat
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免疫原
- Pooled lipid raft fraction isolated from RBL-2H3 cells
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亚型
- IgG2a
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应用备注
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Western blotting: Recommended dilution: 1 μg/mL, positive control: RBL (rat basophilic leukemia) cell line, both reducing and non-reducing conditions.
Flow cytometry: Intracellular staining. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Stabilized with 15 mM sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).
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: "Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis." in: The Journal of biological chemistry, Vol. 283, Issue 16, pp. 10904-18, (2008) (PubMed).
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- PLSCR1 (phospholipid Scramblase 1 (PLSCR1))
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别名
- PLSCR1
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背景
- Phospholipid scramblase 1,PLSCR1 (phospholipid scramblase 1) is a multiply palmitoylated endofacial plasma membrane protein containing several SH3 and WW domain binding motives. In the plasma membrane, PLSCR1 plays a role in transbilayer lipid redistributions and signal transduction. Nonpalmitoylated PLSCR1, however, is able to be transported into the nucleus and bind DNA. PLSCR1 potentiates the antiviral activity of interferon and its expression is highly induced by interferons and growth factors.,PL scramblase 1, phospholipid scramblase 1
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基因ID
- 117540
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UniProt
- P58195
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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