CAMK2A 抗体 (AA 7-20)
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Quick Overview for CAMK2A 抗体 (AA 7-20) (ABIN1888861)
抗原
See all CAMK2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 7-20
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原理
- Anti-CaMKII Rabbit Polyclonal Antibody
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交叉反应
- 小鸡, Cow, 豚鼠, Hamster, 人, 小鼠, 兔, 大鼠
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纯化方法
- Affinity - Purified
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免疫原
- Synthetic peptide corresponding to aa 7-20 (N-terminus) of rat CaMKII delta isoform conjugated to KLH.
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应用备注
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Immunoblotting: Use at 1-5 μg/mL. A band of ~50-60 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations.
Endusers should determine optimal concentrations for their applications. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Dilute in PBS or medium that is identical to that used in the assay system.
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浓度
- Lot specific
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缓冲液
- PBS, 50 % glycerol, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- This antibody is stable for at least one (1) year at -20°C.
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- CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))
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别名
- CAMK2A
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背景
- Calcium/calmodulin-dependent protein kinase type II subunit α,Calmodulin-dependent protein kinase II (CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+/calmodulin complex. CaMKII is involved in many signaling cascades and is thought to be an important mediator of learning and memory. CaMKII is also necessary for Ca2+ homeostasis and reuptake in cardiomyocytes, chloride transport in epithelia, positive T-cell selection, and CD8 T-cell activation. CaMKII has 28 different isoforms that derive from the alpha, beta, gamma, and delta genes. Misregulation of CaMKII is linked to Alzheimer's disease, Angelman syndrome, and heart arrhythmia.,CaM kinase II subunit α, CaMK-II subunit α, EC 2.7.11.17
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基因ID
- 815
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NCBI登录号
- NP_741960
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途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction
抗原
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