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MTA2 抗体 (AA 652-668)

This anti-MTA2 antibody is a 兔 多克隆 antibody detecting MTA2 in WB, ELISA 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1886893
发货至: 中国

Quick Overview for MTA2 抗体 (AA 652-668) (ABIN1886893)

抗原

See all MTA2 抗体
MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

适用

  • 56
  • 37
  • 36
  • 9
  • 9
  • 9
  • 9
  • 7
  • 7
  • 6
  • 5
  • 5
  • 4
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 55
  • 6

克隆类型

  • 52
  • 9
多克隆

标记

  • 41
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This MTA2 antibody is un-conjugated

应用范围

  • 55
  • 17
  • 13
  • 10
  • 9
  • 8
  • 8
  • 8
  • 7
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 652-668

    交叉反应 (详细)

    No cross response to MTA1.

    纯化方法

    Purified by DEAE column

    免疫原

    Synthetic peptide corresponding to amino acids 652 to 668 of human PID (6), which differ from the mouse sequence by one amino acid.
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid freezing and thawing repeatly.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原

    MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

    别名

    PID

    背景

    The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered.The transcriptional activity of p53 is modulated by protein stability and acetylation.PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex.PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53.Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis.PID/MTA2 is ubiquitously expressed in human tissues.
    Synonyms: PID, MTA2

    分子量

    75 kDa

    途径

    Chromatin Binding
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