MTA2 抗体 (AA 652-668)
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北京 101111
Quick Overview for MTA2 抗体 (AA 652-668) (ABIN1886893)
抗原
See all MTA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 652-668
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交叉反应 （详细）
- No cross response to MTA1.
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纯化方法
- Purified by DEAE column
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免疫原
- Synthetic peptide corresponding to amino acids 652 to 668 of human PID (6), which differ from the mouse sequence by one amino acid.
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anti-Metastasis Associated 1 Family, Member 2 (MTA2) antibody
MTA2 适用: 人 WB, IHC, IF, ChIP 宿主: 兔 Monoclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 60-180) antibodyMTA2 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) antibodyKD Validated MTA2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB400 unconjugated Recombinant Antibody
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, Cow, 马, 兔, 山羊, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 1-394) antibodyMTA2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 516-544), (C-Term) antibodyMTA2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20031 unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 山羊, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (AA 398-447) antibodyMTA2 适用: 人, 斑马鱼, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Metastasis Associated 1 Family, Member 2 (MTA2) (C-Term) antibodyMTA2 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))
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别名
- PID
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背景
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The p53 tumor-suppressor gene integrates numerous signals that control cell life and death.Several novel molecules involved in p53 pathway, including Chk2, p53R2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered.The transcriptional activity of p53 is modulated by protein stability and acetylation.PID/MTA2, also termed MTA1-L1, was found to be a subunit of nucleosome remodeling and deacetylating (NRD/NuRD) complex.PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53.Deacetylation of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis.PID/MTA2 is ubiquitously expressed in human tissues.
Synonyms: PID, MTA2 -
分子量
- 75 kDa
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途径
- Chromatin Binding
抗原
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