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Caspase 10 抗体 (AA 505-521)

This anti-Caspase 10 antibody is a 兔 多克隆 antibody detecting Caspase 10 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN1886883
发货至: 中国

Quick Overview for Caspase 10 抗体 (AA 505-521) (ABIN1886883)

抗原

See all Caspase 10 (CASP10) 抗体
Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

适用

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宿主

  • 64
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克隆类型

  • 59
  • 14
多克隆

标记

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This Caspase 10 antibody is un-conjugated

应用范围

  • 39
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Western Blotting (WB), ELISA
  • 抗原表位

    • 16
    • 6
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    AA 505-521

    特异性

    Antibody only recognizes FLICE2 form of caspase-10.

    纯化方法

    Purified by DEAE column

    免疫原

    Peptide corresponding to amino acids 505 to 521 of human FLICE2.
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid freezing and thawing repeatly.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原

    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

    别名

    Caspase-10

    背景

    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family.A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch4 and renamed as caspase-10.Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors.Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis.Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which causes the proteolytic cleavage of many key proteins such as PARP.Cleavage of PARP occurs in many different systems during apoptosis and is the hallmark of programmed cell death.Caspase-10 is expressed in many tissues and cell lines.
    Synonyms: Casp-10, FLICE2

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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