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FLIP 抗体 (AA 449-465)

This anti-FLIP antibody is a 兔 多克隆 antibody detecting FLIP in WB, ELISA 和 ICC. Suitable for 小鼠.
产品编号 ABIN1886881
发货至: 中国

Quick Overview for FLIP 抗体 (AA 449-465) (ABIN1886881)

抗原

See all FLIP (CFLAR) 抗体
FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This FLIP antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

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    AA 449-465

    特异性

    FLIP has short form (FLIPS) and long form (FLIPL) and antibody recognizes the FLIPL only.

    纯化方法

    Purified by DEAE column

    免疫原

    Peptide corresponding to amino acids 449 to 465 of mouse FLIPL/CASHa.
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid freezing and thawing repeatly.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原

    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

    别名

    FLIP

    背景

    Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain (DD) containing adapter molecules and members of the ICE/CED-3 protease family.Caspases-8 (FLICE) and -10 (FLICE2) are two pivotal members in the ICE/CED-3 protease family.FLICE-inhibitory proteins were identified in virus and human and designated v-FLIPs and FLIP respectively.The human FLIP was also cloned by several labs independently and termed Casper , I-FLICE, FLAME-1, CASH, CLARP and MRIT.FLIP contains two death effector domains (DEDs) and a caspase-like domain.FLIP interacts with adapter protein FADD and caspase-8 and 10, and potently inhibits apoptosis induced by all known death receptors CD95, DR3, TRAIL-R and TNFR1.
    Synonyms: I-FLICE

    分子量

    55 kDa

    NCBI登录号

    NP_997536

    途径

    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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