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BACE2 抗体 (AA 44-59)

This anti-BACE2 antibody is a 兔 多克隆 antibody detecting BACE2 in WB, IHC 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1886880
发货至: 中国

Quick Overview for BACE2 抗体 (AA 44-59) (ABIN1886880)

抗原

See all BACE2 抗体
BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

适用

  • 47
  • 35
  • 12
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 69
  • 3
  • 1

克隆类型

  • 71
  • 2
多克隆

标记

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  • 12
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  • 2
  • 1
  • 1
  • 1
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  • 1
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  • 1
This BACE2 antibody is un-conjugated

应用范围

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  • 29
  • 27
  • 13
  • 13
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  • 11
  • 8
  • 8
  • 4
  • 3
  • 3
  • 3
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 44-59

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    Synthetic peptide corresponding to amino acids 44 to 59 of human BACE2.
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid freezing and thawing repeatly.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原

    BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))

    别名

    BACE2

    背景

    Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease.Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases.The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2).A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1.BACE2 also cleaves APP at beta-site and at a different site within Abeta.BACE2 locates on chromosome 21q22.3, the so-called 'Down critical region', suggesting that BACE2 and Abeta may also contribute to the pathogenesis of Down syndrome.
    Synonyms: Asp2
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