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GFRA2 抗体 (AA 377-391)

This 兔 多克隆 anti-GFRA2 antibody specifically detects GFRA2 in WB, ELISA 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1886875
发货至: 中国
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Quick Overview for GFRA2 抗体 (AA 377-391) (ABIN1886875)

抗原

See all GFRA2 抗体
GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

适用

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  • 2
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人, 小鼠, 大鼠

宿主

  • 54
  • 2
  • 1
  • 1

克隆类型

  • 56
  • 1
多克隆

标记

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  • 1
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This GFRA2 antibody is un-conjugated

应用范围

  • 47
  • 21
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  • 13
  • 7
  • 7
  • 7
  • 4
  • 4
  • 3
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  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

    • 15
    • 7
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    AA 377-391

    纯化方法

    Purified by DEAE column

    免疫原

    Peptide corresponding to amino acids 377 to 391 of human GFR alpha 2.The amino acid sequences of immunogenic peptide are identical to those of mouse and rat.
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid freezing and thawing repeatly.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C for short term use.Store at -20 °C for long term preservation.
  • 抗原

    GFRA2 (GDNF Family Receptor alpha 2 (GFRA2))

    别名

    GFR alpha 2

    背景

    Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play key roles in the control of vertebrate neuron survival and differentiation.Physiological responses to NTN require the presence of a novel glycosylphosphadidylinositol linked protein NTNRalpha, which is a cell surface receptor for NTN.The cDNAs encoding NTNRalpha from human, rat, chicken, and mouse have been cloned recently.NTNRalpha was also termed GDNFRbeta, Ret ligand 2 (RETL2) or TGFbeta-related neurotrophic factor receptor 2 (TrnR2) and nominated as GFRalpha-2 recently.GFRalpha-2 binds NTN and mediates activation of RET receptor tyrosine kinase by both NTN and GDNF.Thus, NTN, GFRalpha-2, and the Ret PTK form a complex to transduce NTN signal and to mediate NTN function.
    Synonyms: GFRa-2, GDNFRb, GDNFRbeta

    分子量

    52 kDa
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