CIDEA
适用: 小鼠, 大鼠
IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 750
限制
仅限研究用
状态
Liquid
缓冲液
PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项
Avoid freezing and thawing repeatly.
储存条件
4 °C/-20 °C
储存方法
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
抗原
CIDEA
(Cell Death-Inducing DFFA-Like Effector A (CIDEA))
别名
CIDE-A
背景
Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands.Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases.These death signals finally cause the degradation of chromosomal DNA by activated DNase.DFF45/ICAD has been identified as inhibitor of caspase activated DNase DFF40/CAD.DFF45 related proteins CIDE-A and CIDE-B (for cell death-inducing DFF-like effector A and B) were recently identified.CIDE contains a new type of domain termed CIDE-N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD.Expression of CIDE-A induces DNA fragmentation and activates apoptosis, which is inhibited by DFF45.CIDE-A is a DFF45-inhibitable effector that promotes cell death and DNA fragmentation.CIDE-A is expressed in many tissues.