DR4 抗体 (AA 1-20)
Quick Overview for DR4 抗体 (AA 1-20) (ABIN1886840)
抗原
See all DR4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-20
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交叉反应 （详细）
- DR4 antibody has no cross reaction to DR5.
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纯化方法
- Purified by DEAE column
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免疫原
- Peptide corresponding to amino acid 1 to 20 of human DR4 mature protein.
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anti-Drought-Repressed 4 Protein (DR4) (AA 401-468) antibody
DR4 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (C-Term) antibodyDR4 适用: 人, 猴 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (C-Term) antibodyDR4 适用: 人, 小鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Drought-Repressed 4 Protein (DR4) (AA 401-450) antibodyDR4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid freezing and thawing repeatly.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- DR4 (Drought-Repressed 4 Protein (DR4))
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别名
- DR4
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背景
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Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms.Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas.A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4).The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family.DR4 is also called TRAIL receptor-1 (TRAIL-R1).DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus.Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kappaB activation in many tissues and cells.
Synonyms: TRAIL-R1 -
分子量
- 57 kDa
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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