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Ki-67 抗体 (N-Term)

This 兔 多克隆 anti-Ki-67 antibody specifically detects Ki-67 in IHC, IF 和 ICC. The antibody is reactive with 人 samples.
产品编号 ABIN1886792
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Ki-67 抗体 (N-Term) (ABIN1886792)

抗原

See all Ki-67 (MKI67) 抗体
Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

适用

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宿主

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克隆类型

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多克隆

标记

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This Ki-67 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 30
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    N-Term

    免疫原

    KLH conjugated synthetic peptide derived from human Ki67 N-terminus
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.100-1.500
    Immunohistochemistry 1.100-1.500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.01 M PBS, pH 7.4 with 10 mg/ml BSA and 0.1 % Sodium azide

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C/1 year

    有效期

    12 months
  • 抗原

    Ki-67 (MKI67) (Antigen Identified By Monoclonal Antibody Ki-67 (MKI67))

    别名

    Ki67

    背景

    Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase).It is absent in resting (G0) cells.Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index).In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index.The correlation between low Ki67 index and histologically low grade tumours is strong.Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.Sueishi M.et al.J.Biol.Chem.275:28888-28892(2000) Takagi M.et al.J.Biol.Chem.276:25386-25391(2001) Beausoleil S.A.et al.Proc.Natl.Acad.Sci.U.S.A.101:12130-12135(2004) Olsen J.V.et al.Cell 127:635-648(2006)
    Synonyms: KIA, Ki-67, Ki67, MKI67

    分子量

    358 kDa

    UniProt

    P46013

    途径

    Glycosaminoglycan Metabolic Process
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