Cofilin 2 抗体 (AA 92-152)
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北京 101111
Quick Overview for Cofilin 2 抗体 (AA 92-152) (ABIN1886714)
抗原
See all Cofilin 2 (CFL2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 92-152
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 92 and 152 of Cofilin 2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Cofilin 2 (CFL2)
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别名
- Cofilin 2
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背景
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Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner.(Gillett et al., 1996 [PubMed 8800436]).Cofilin-2 is a member of the AC group of proteins that also includes cofilin-1 (CFL1) and destrin (DSTN, MIM 609114), all of which regulate actin-filament dynamics (Bamburg et al., 1999 [PubMed 10461190], Maciver and Hussey, 2002).The CFL2 gene encodes a skeletal muscle-specific isoform (Vartiainen et al., 2002 [PubMed 11809832]) localized to the thin filaments, where it exerts its effect on actin, in part through interactions with tropomyosins (Ono and Ono, 2002 [PubMed 11901171]).[supplied by OMIM]
Synonyms: NEM7 -
分子量
- 19 kDa
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基因ID
- 1073
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NCBI登录号
- NP_619579, NM_138638
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途径
- Caspase Cascade in Apoptosis
抗原
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