Perforin 1 抗体 (AA 9-184)
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北京 101111
Quick Overview for Perforin 1 抗体 (AA 9-184) (ABIN1886703)
抗原
See all Perforin 1 (PRF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 9-184
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 9 and 184 of Perforin 1
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))
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别名
- Perforin 1
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背景
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The protein encoded by this gene has structural and functional similarities to complement component 9 (C9).Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells.This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis.Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq]
Synonyms: HPLH2, MGC65093, P1, PFP -
分子量
- 61 kDa
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基因ID
- 5551
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NCBI登录号
- NM_005041, NP_005032
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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