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Perforin 1 抗体 (AA 9-184)

This anti-Perforin 1 antibody is a 兔 多克隆 antibody detecting Perforin 1 in WB. Suitable for 人.
产品编号 ABIN1886703
发货至: 中国

Quick Overview for Perforin 1 抗体 (AA 9-184) (ABIN1886703)

抗原

See all Perforin 1 (PRF1) 抗体
Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

适用

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宿主

  • 62
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克隆类型

  • 65
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多克隆

标记

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This Perforin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 9-184

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 9 and 184 of Perforin 1
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    Perforin 1 (PRF1) (Perforin 1 (Pore Forming Protein) (PRF1))

    别名

    Perforin 1

    背景

    The protein encoded by this gene has structural and functional similarities to complement component 9 (C9).Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells.This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis.Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood.Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq]
    Synonyms: HPLH2, MGC65093, P1, PFP

    分子量

    61 kDa

    基因ID

    5551

    NCBI登录号

    NM_005041, NP_005032

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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