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VAV1 抗体 (AA 83-538)

The 兔 多克隆 anti-VAV1 antibody (ABIN1886679) specifically detects VAV1 in WB 和 IHC. The antibody is reactive with 人 samples.
产品编号 ABIN1886679
发货至: 中国
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Quick Overview for VAV1 抗体 (AA 83-538) (ABIN1886679)

抗原

See all VAV1 抗体
VAV1 (Vav 1 Oncogene (VAV1))

适用

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宿主

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克隆类型

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多克隆

标记

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This VAV1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 83-538

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 83 and 538 of Human VAV1
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    VAV1 (Vav 1 Oncogene (VAV1))

    别名

    VAV1

    背景

    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins.The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation.This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1.Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.[provided by RefSeq]
    Synonyms: VAV

    分子量

    98 kDa

    基因ID

    7409

    NCBI登录号

    NM_005428, NP_005419

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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