NAPA 抗体 (AA 78-269)
Our Local Distributor
北京 101111
Quick Overview for NAPA 抗体 (AA 78-269) (ABIN1886662)
抗原
See all NAPA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 78-269
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 78 and 269 of Human NAPA
-
-
-
-
应用备注
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- NAPA (N-Ethylmaleimide-Sensitive Factor Attachment Protein, alpha (NAPA))
-
别名
- alpha SNAP
-
背景
-
The 'SNARE hypothesis' is a model explaining the process of docking and fusion of vesicles to their target membranes.According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern theof vesicle targeting and docking through mutual recognition.Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex.Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport.The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively.Platelets contain some of the same proteins, including NSF, p115/TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types.Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different.[provided by RefSeq]
-
分子量
- 33 kDa
-
基因ID
- 8775
-
NCBI登录号
- NM_003827, NP_003818
-
途径
- Synaptic Vesicle Exocytosis, Asymmetric Protein Localization
抗原
-