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POLG 抗体 (AA 779-1191)

This anti-POLG antibody is a 兔 多克隆 antibody detecting POLG in WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN1886660
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for POLG 抗体 (AA 779-1191) (ABIN1886660)

抗原

See all POLG 抗体
POLG (Polymerase (DNA Directed), gamma (POLG))

适用

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宿主

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克隆类型

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多克隆

标记

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This POLG antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 779-1191

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 779 and 1191 (P54098) of DNA polymerase gamma
  • 应用备注

    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.250
    Immunofluorescence: 1.100-1.200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    Biohazard Informations: This product contains thimerosal which is hazardous.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    POLG (Polymerase (DNA Directed), gamma (POLG))

    别名

    DNA Polymerase gamma

    背景

    Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit.The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase.The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic.Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE).Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]

    分子量

    140 kDa

    基因ID

    5428

    NCBI登录号

    NM_002693, NP_002684
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