POLG 抗体 (AA 779-1191)
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北京 101111
Quick Overview for POLG 抗体 (AA 779-1191) (ABIN1886660)
抗原
See all POLG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 779-1191
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 779 and 1191 (P54098) of DNA polymerase gamma
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- POLG (Polymerase (DNA Directed), gamma (POLG))
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别名
- DNA Polymerase gamma
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背景
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Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit.The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase.The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic.Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE).Two transcript variants encoding the same protein have been found for this gene.[provided by RefSeq]
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分子量
- 140 kDa
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基因ID
- 5428
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NCBI登录号
- NM_002693, NP_002684
抗原
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