BCL2L10 抗体 (AA 70-133)
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北京 101111
Quick Overview for BCL2L10 抗体 (AA 70-133) (ABIN1886624)
抗原
See all BCL2L10 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 70-133
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 70 and 133 of BCL2L10
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
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别名
- BCL2L10
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背景
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The protein encoded by this gene belongs to the BCL-2 protein family.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains.This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX.Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation.The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.[provided by RefSeq]
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分子量
- 23 kDa
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基因ID
- 10017
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NCBI登录号
- NM_020396, NP_065129
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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