TYK2 抗体 (AA 680-1176)
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Quick Overview for TYK2 抗体 (AA 680-1176) (ABIN1886613)
抗原
See all TYK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 680-1176
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 680 and 1176 of TYK2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- TYK2 (Tyrosine Kinase 2 (TYK2))
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别名
- TYK2
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背景
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This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families.This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits.It is also component of both the type I and type III interferon signaling pathways.As such, it may play a role in anti-viral immunity.A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E.[provided by RefSeq]
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分子量
- 134 kDa
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基因ID
- 7297
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NCBI登录号
- NM_003331, NP_003322
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途径
- JAK/STAT Signaling, Hepatitis C
抗原
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