Haptoglobin 抗体 (AA 57-392)
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Quick Overview for Haptoglobin 抗体 (AA 57-392) (ABIN1886560)
抗原
See all Haptoglobin (HP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 57-392
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 57 and 392 of Haptoglobin
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Haptoglobin (HP)
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别名
- Haptoglobin
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背景
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This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin.Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin.Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia.This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria.A similar duplicated gene is located next to this gene on chromosome 16.Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 45 kDa
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基因ID
- 3240
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NCBI登录号
- NP_005134, NM_005143
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途径
- Transition Metal Ion Homeostasis
抗原
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