RGS14 抗体 (AA 504-566)
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北京 101111
Quick Overview for RGS14 抗体 (AA 504-566) (ABIN1886520)
抗原
See all RGS14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 504-566
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Synthetic peptide contain a sequence corresponding to a region within amino acids 504 and 566 of Human RGS14
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
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别名
- RGS14
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背景
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This gene encodes a member of the regulator of G-protein signaling family.This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain.The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits.Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP.This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.[provided by RefSeq]
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分子量
- 61 kDa
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基因ID
- 10636
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NCBI登录号
- NM_006480, NP_006471
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
抗原
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