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FGD4 抗体 (AA 49-297)

FGD4 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1886512
发货至: 中国
  • 抗原 See all FGD4 抗体
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    抗原表位
    • 8
    • 8
    • 7
    • 2
    • 1
    AA 49-297
    适用
    • 23
    • 2
    • 2
    宿主
    • 23
    克隆类型
    • 23
    多克隆
    标记
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This FGD4 antibody is un-conjugated
    应用范围
    • 22
    • 13
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein fragment contain a sequence corresponding to a region within amino acids 49 and 297 of FGD4
    Top Product
    Discover our top product FGD4 Primary Antibody
  • 应用备注
    Suggested dilutions:
    Western blotting: 1.500-1.3000
    Immunohistochemistry: 1.100-1.500
    Immunofluorescence: 1.100-1.200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    Biohazard Informations: This product contains thimerosal which is hazardous.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))
    别名
    FGD4 (FGD4 产品)
    别名
    CMT4H antibody, FRABP antibody, ZFYVE6 antibody, 9030023J02Rik antibody, 9330209B17Rik antibody, Frabp antibody, FYVE, RhoGEF and PH domain containing 4 antibody, FGD4 antibody, Fgd4 antibody
    背景
    This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape.This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes.This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP.The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract.Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system.[provided by RefSeq]
    分子量
    87 kDa
    基因ID
    121512
    NCBI登录号
    NM_139241, NP_640334
    途径
    Neurotrophin Signaling Pathway
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