Desmocollin 2 抗体 (AA 480-676)
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Quick Overview for Desmocollin 2 抗体 (AA 480-676) (ABIN1886508)
抗原
See all Desmocollin 2 (DSC2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 480-676
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 480 and 676 of Desmocollin 2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- Desmocollin 2 (DSC2)
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别名
- Desmocollin 2
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背景
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The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily.These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation.The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11.Alternative splicing results in two transcript variants encoding distinct isoforms.[provided by RefSeq]
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分子量
- 94 kDa
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基因ID
- 1824
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NCBI登录号
- NM_004949, NP_004940
抗原
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