NXF1 抗体 (AA 449-598)
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Quick Overview for NXF1 抗体 (AA 449-598) (ABIN1886478)
抗原
See all NXF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 449-598
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纯化方法
- Affinity purified by Protein A.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 449 and 598 of TAP
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 1 x PBS, 1 % BSA, 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- NXF1 (Nuclear RNA Export Factor 1 (NXF1))
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别名
- nuclear RNA export factor 1
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背景
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This gene is one member of a family of nuclear RNA export factor genes.Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins.The LRRs and NTF2-like domains are required for export activity.Alternative splicing seems to be a common mechanism in this gene family.The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA.It is the vertebrate homologue of the yeast protein Mex67p.The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.Alternative splicing results in multiple transcript variants.[provided by RefSeq]
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分子量
- 70 kDa
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基因ID
- 10482
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NCBI登录号
- NP_006353, NM_006362
抗原
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