Exportin 2 抗体 (AA 222-439)
Our Local Distributor
北京 101111
Quick Overview for Exportin 2 抗体 (AA 222-439) (ABIN1886219)
抗原
See all Exportin 2 (CSE1L) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 222-439
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 222 and 439 of CSE1L
-
-
-
-
应用备注
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
-
别名
- CSE1L
-
背景
-
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer.Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex.After translocation, RanGTP binds importin-beta and displaces importin-alpha.Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind.The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1.In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.[provided by RefSeq]
-
分子量
- 110 kDa
-
基因ID
- 1434
-
NCBI登录号
- NP_001307, NM_001316
-
途径
- Protein targeting to Nucleus
抗原
-