Factor VII 抗体 (AA 209-444)
Our Local Distributor
北京 101111
Quick Overview for Factor VII 抗体 (AA 209-444) (ABIN1886186)
抗原
See all Factor VII (F7) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 209-444
-
纯化方法
- Purified by antigen-affinity chromatography.
-
免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII
-
-
-
-
应用备注
-
Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
-
储存液
- Thimerosal (Merthiolate)
-
注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
-
-
- Factor VII (F7) (Coagulation Factor VII (F7))
-
别名
- Factor VII
-
背景
-
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis.This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis.Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond.In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa.Alternative splicing of this gene results in 2 transcripts.Defects in this gene can cause coagulopathy.[provided by RefSeq]
-
分子量
- 52 kDa
-
基因ID
- 2155
-
NCBI登录号
- NP_000122, NM_000131
-
途径
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
抗原
-