alpha Actinin 4 抗体 (AA 206-512)
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- 抗原 See all alpha Actinin 4 (ACTN4) 抗体
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
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抗原表位
- AA 206-512
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This alpha Actinin 4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 206 and 512 of alpha Actinin 4
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- Discover our top product ACTN4 Primary Antibody
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- 应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- 抗原
- alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
- 别名
- alpha Actinin 4 (ACTN4 产品)
- 别名
- fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody
- 背景
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Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins.Alpha actinin is an actin-binding protein with multiple roles in different cell types.In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane.In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.Mutations in this gene have been associated with focal and segmental glomerulosclerosis.[provided by RefSeq]
- 分子量
- 105 kDa
- 基因ID
- 81
- 途径
- Proton Transport
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