MMP2 抗体 (AA 193-545)
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北京 101111
Quick Overview for MMP2 抗体 (AA 193-545) (ABIN1886151)
抗原
See all MMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 193-545
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 193 and 545 of Human MMP2
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应用备注
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- MMP2 (Matrix Metalloproteinase 2 (MMP2))
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别名
- MMP2
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背景
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis.Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes.The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]
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分子量
- 74 kDa
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基因ID
- 4313
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NCBI登录号
- NM_004530, NP_004521
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途径
- Activation of Innate immune Response
抗原
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