CLP1 抗体 (AA 142-341)
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北京 101111
Quick Overview for CLP1 抗体 (AA 142-341) (ABIN1886042)
抗原
See all CLP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 142-341
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纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 142 and 341 of HEAB
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anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (Center) antibody
CLP1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) antibodyKD Validated CLP1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB3085 unconjugated Recombinant Antibody
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 316-425) antibodyCLP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 8D5 unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 316-425) antibodyCLP1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 1-425) antibodyCLP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Cleavage and Polyadenylation Factor I Subunit 1 (CLP1) (AA 1-425) antibodyCLP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Suggested dilutions:
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200 -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- Biohazard Informations: This product contains thimerosal which is hazardous.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- CLP1 (Cleavage and Polyadenylation Factor I Subunit 1 (CLP1))
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别名
- HEAB
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背景
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Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids.dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component.Appears to have roles in both tRNA splicing and mRNA 3'-end formation.Component of the tRNA splicing endonuclease complex.Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing, this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA.Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation.Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC).However endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.
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分子量
- 48 kDa
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基因ID
- 10978
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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